The main complaints in fillers are short duration and low volume effect, having both a direct impact on the total cost of treatment paid by the patient.
Having this in mind and after five years of research, in 2005 ADODERM developed the 'Monophasic Particle Technology' (MPT), offering multiple benefits for doctors as well as for patients.
Non cross-linked hyaluronic acid in its basic state.
preventing the fast degradation of hyaluronic acid in the skin.
Particulisation and homogenisation
WHY IS THE CROSS LINKING PROCESS SO IMPORTANT?
Due to the natural aging process of the human skin hyaluronic acid (HA) is quickly degradated.
As the best and safetest way for recovering loss of facial volume is the injection of HA into the different skin layers, to prevent the fast degradation it is important to cross-linked HA.
By increasing the cross linkage of the different units of HA, a stronger barrier against the normal degradation is created. In other
words, more links between the HA units means higher percentage of cross-link.
The traditional processes for obtaining HA do not achieve the optimal durability after injection in the skin. This is why ADODERM GmbH has chosen to develop its own process for a longer durability in the skin.
WHAT IS THE DIFFERENCE BETWEEN CROSS LINKAGE AND CONCENTRATION OF HYALURONIC ACID?
Cross linkage of HA extends the durability of the treatment. It refers to the connection between the individual units within the gel. Higher the cross-link, longer it will stay inside the body.
The concentration of HA points out to he amount of HA powder mixed with a solution. It is indicated in mg/ml.
At lower the concentration, less water will be absorbed within the skin.Less volume but
also shorter duration.
As the skin thickness differs all over the face, it is vital to adapt the concentration of HA to the intended area.
In indications with very thin skin, like lips or tear trough, only HA with low concentration should be injected to prevent unnatural results.
VARIODERM® and HYABELL® products offer a range of high and low concentrations of HA with excellent visco-elastic features. Low concentrations with low elasticity are meant for sensitive areas, while high concentrations with high elasticity are meant for the creation of facial volume.
THE PARTICULISATION AND HOMOGENISATION OF ADODERM HYALURONIC ACID GELS
In the third stage of our process, each cross-linked concentration is formed into an homogeneous and stabilized gel of HA particles.
As a result we achieve for each product a unique rheological features known as G', G'', G* and tanδ.
With this difference in rheology, we adapt the gel to any particular facial treatment.
The final key feature, is the injectability or extrusion force. Both VARIODERM® and HYABELL® have a soft and highly homogeneous extrusion force, that is achieved thanks to our "Monophasic Particle Technology” (MPT).
QUALITY AND SAFETY STANDARDS
The term 'Made in Germany' is not just a marketing tool. It is a seal of highest quality standards and compliance with most strict regulations. Before the release of each syringe we perform numerous tests and optical controls to guarantee the pureness of our gels.
We commit to German and European regulations and controls to guarantee the performance, safety and
quality of ADODERM products to doctors and patients worldwide.